Wow, you guys really have any kind of hope for this thing??
Considering how most videogames adaptations end up being, we have more reasons to be depressed than excited about it

Of all the videogame movies I've seen the only one that came close to the real thing was Silent Hill, and to a lesser extend the first Mortal Kombat, but it's hard to get it wrong with a game that's all about random fights. Yet, they managed to produce a really awful sequel.
Anyway, I don't want to be a downer since everyone is putting effort into guessing good actors.
I'd like to see an adaptation of MGS1. You know, it's the start, the most fresh one and it has some really good scenes to steal from (like Sniper Wolf's death, or Psycho Mantis' and, of course, the Liquid cover).
It's a shame Clint Eastwood is so old now, he could have been a killer Revolver Ocelot, with a Magnum 44, lol!